Luigi Adamo

This study identifies metabolic and redox pathway dysregulation in HIV-associated coronary endothelial dysfunction using proteomics and MRI.

This study uses spatial transcriptomics to show that myocarditis involves widespread molecular changes in cardiomyocytes, not just immune cell areas.

This study shows GSNOR deletion protects male cardiac function with age but may worsen female cardiac function by removing an age-related SNO imbalance.

This study shows that macrophages with constitutive mTORC1 activation via TSC2 deletion reduce inflammation and improve cardiac function after ischemia-reperfusion injury by increasing GPNMB expression.

This study identifies immune-related gene expression changes in asymptomatic Chagas cardiomyopathy patients, suggesting unique immune mechanisms in early disease progression.

This paper develops a reproducible murine model of T. brucei-induced myocarditis and cardiac dysfunction, showing immune-mediated cardiac damage and elevated NT-proBNP levels.

This study shows splenic follicular B cells worsen heart failure after MI by presenting cardiac antigens via MHC II, promoting adverse cardiac remodeling.

The paper identifies B cell gene expression and interactions in healthy and diseased human myocardium, finding disease-specific changes in DCM and ARVC.

This study shows that overexpressing adenylyl cyclase type-8 in cardiomyocytes activates RelA and causes myocardial and systemic inflammation, leading to accelerated aging and reduced lifespan.