Cancer BiologyCancer ResearchPeer-reviewed
Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer
Mustafa Emre Gedik, Özge Saatci, Nathaniel P. Oberholtzer…·Özgür Şahin
This study shows that T-DM1 induces immunogenic cell death (ICD) in HER2-positive breast cancer, which is lost in resistance, and that targeting TACC3 restores ICD and enhances T-DM1 response.
46 citationstop 2%