Author

Sridevi Challa

The University of Texas Southwestern Medical CenterORCID 0000-0002-5308-9243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Cristel V. CamachoiD· 3 shared W. Lee KrausiD· 3 shared Alexandra N. SpirtosiD· 1 shared Amy L. Whitaker· 1 shared Jayanthi Sivasothy LeaiD· 1 shared Jonathan C AbshieriD· 1 shared Jonathan C. Abshier· 1 shared Keun W. Ryu· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

Cristel V. CamachoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyJournal of Biological ChemistryPeer-reviewedSep 8, 2026

PARP16 is a Druggable Regulator of Ribosome MARylation and Protein Homeostasis in Ovarian Cancer Cells

Sridevi Challa, Morgan Dasovich, Jonathan C Abshier…·W. Lee Kraus

This study investigates PARP16's role in ovarian cancer by showing that inhibiting it with DB008 disrupts ribosome MARylation, impairs protein homeostasis, and reduces tumor growth.

DOI 10.1016/j.jbc.2026.113540

humanproteomics

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Cancer BiologybioRxivPreprintAug 20, 2024

RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells

Alexandra N. Spirtos, Marwa W. Aljardali, Sridevi Challa…·Cristel V. Camacho

This study shows that RBN-2397, a PARP7 inhibitor, reduces ovarian cancer cell proliferation and migration, and synergizes with paclitaxel to enhance these effects.

6 citations

humanbulk RNA-seq

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Synthetic BiologyeLifePeer-reviewedMar 23, 2022

Development and Characterization of PAR-Trackers: New Tools for Detecting Poly(ADP-ribose) In Vitro and In Vivo

Sridevi Challa, Keun W. Ryu, Amy L. Whitaker…·W. Lee Kraus

The paper develops and characterizes PAR-Trackers, new tools for detecting poly(ADP-ribose) in vitro and in vivo, showing improved sensitivity and spatial-temporal resolution.

21 citations

experimental assay

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