Sharon G. Wolf

This paper introduces parallax-filtered cryo-STET imaging to enhance contrast in thick biological specimens, demonstrating improvements over traditional STEM methods.

The paper uses cryo-STET to study mitochondrial fission in MFF mutant cells under ATP-depleting conditions, revealing fission progression without MFF.

This study identifies Yet3 as a protein that recruits sterol biosynthesis enzymes to ER contact sites, enabling on-demand sterol production and influencing organellar structure and function.