German Nudelman

This study generates twelve SARS-CoV-2 viruses with mutations in individual proteins and shows that many have interferon-antagonizing activity and immunosuppressive effects in human cells and mice, with NSP1 and NSP15 having the greatest impact.

This study identifies tissue-specific lncRNA responses to endurance exercise in rats, revealing sex differences and potential therapeutic implications.

This study examines how acute endurance and resistance exercise alter alternative splicing in human skeletal muscle, adipose tissue, and blood, identifying 5102 differential splicing events and their regulatory mechanisms.

The paper identifies four activin-sensitive enhancers upstream of the murine Fshb gene, showing differential regulation by SMAD2/3 and FOXL2 in gonadotropes.

This study identifies how genetic and environmental factors shape the human immune cell epigenome through differential methylation and chromatin accessibility changes.

This study identifies a shared infiltrative signature in glioblastoma at the resection margin using spatial multi-omics data and validates EGFR as a key marker.

This paper provides a comprehensive guide for quality control metrics and mitigation strategies for 11 epigenetics and transcriptomics assays to improve exposure signature discovery.

This study examines how endurance exercise training affects rat subcutaneous white adipose tissue, revealing sex-specific molecular responses and differences in adiposity and metabolism.

This study compares host module activation patterns and temporal dynamics across four influenza H1N1 viruses to identify conserved and differentially regulated immune responses.

The paper isolates and profiles cell types in human TLE samples, revealing dysregulated pathways and an immature glial phenotype.

This study improves zebrafish transcriptome annotation using long-read sequencing, identifying novel transcripts and isoforms, and validating them through computational and experimental methods.