Cell surface proteomics of patient-derived malignant rhabdoid tumor organoids identifies ROBO1 as potential CAR T cell target for pediatric solid tumors.
Juliane L. Buhl, Jannet Koelewijn, Charlotte op ’t Hoog…·Claudia Y. Janda
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Princess Máxima CenterORCID 0000-0002-5395-8293Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Juliane L. Buhl, Jannet Koelewijn, Charlotte op ’t Hoog…·Claudia Y. Janda
Xiang Fang, Benjamin Chalopin, S. Seyda Gokturk…·Claudia Y. Janda
The paper maps epitopes of B7-H3-targeting VHH-Fcs to identify isoform-selective binders for antibody-drug conjugate development.
Lindy L. Visser, Stephanie A Schubert, Baojie Zhang…·Claudia Y. Janda
This study identifies lineage-associated tumor cell states in pediatric osteosarcoma that correlate with clinical outcomes and guide immunotherapeutic target selection.
Li Yang, Lulu Huang, Fenna L. H. van Rijt…·Claudia Y. Janda
This paper develops a Wnt-IL-13 fusion protein that activates tuft cells to enhance intestinal regeneration in human organoids.
Kelly Warmink, Philip Lijnzaad, Stephanie A Schubert…·Claudia Y. Janda
This study investigates dexamethasone-induced bone toxicity in developing bones using single-cell transcriptomics in mice, revealing reduced osteoblast and chondrocyte populations and disrupted B cell development.