Xinjun He

This paper develops an ELISA assay for EV quantification to improve accuracy in large-scale EV manufacturing by reducing interference from contaminants.

This study shows that mesenchymal stem cell-derived extracellular vesicles reduce psoriasis symptoms in a mouse model induced by imiquimod.

This paper introduces a novel large-scale EV production strategy with upstream fed-batch suspension cell culture and downstream chromatographic purification for clinical applications.

This study shows that mesenchymal stem cell-derived extracellular vesicles reduce symptoms in a dextran sulfate sodium-induced ulcerative colitis mouse model by repairing colon mucosa and reducing macrophage infiltration.

This study demonstrates that extracellular vesicles loaded with KRAS-targeting siRNA can inhibit tumor growth in mouse models, both intratumorally and intravenously.