BiochemistrybioRxivPreprint
FAST RESENSITIZATION OF G PROTEIN-COUPLED RECEPTORS REQUIRESTHEIR PI(4,5)P2-DEPENDENT SORTING INTO AN AP2 POSITIVE COMPARTMENT
Gergő Gulyás, Takashi Baba, Dániel J. Tóth…·Tamás Balla
This study shows that GPCRs regain G protein signaling without endocytosis by sorting into an AP2-positive plasma membrane compartment, regulated by PI(4,5)P2 and beta-arrestins.
DOI 10.1101/2025.03.28.645988