Berna Doğan

This study identifies potential USP7 inhibitors through virtual screening and molecular simulations, finding 12 compounds with favorable binding and anticancer activity.

This study evaluates the binding constants of nine BCL-2 inhibitors using DSC, showing agreement with prior biological assays and simulations, and suggests DSC's utility in high-throughput drug screening.

The paper develops machine learning models to predict compound selectivity against hDAC1 and hDAC6 isoforms using bioactivity data.

The paper characterizes the structure and function of AstR-C in T.pit, identifying Q2716.55 as critical for G protein-dependent activation.