Vijaya Pandey

This paper identifies that truncating variants in KAT6A cause two distinct neurodevelopmental disorders with opposing gene regulatory and metabolic effects, highlighting the need for variant-level stratification in therapy development.

The paper identifies a conserved vesicular circuit that maintains heme homeostasis by rerouting intracellular heme flux, showing its role in metabolic adaptation across species.

This study identifies FBXO42's role in regulating PPP4C and p53 signaling, showing its importance in cancer cell survival through genetic and proteomic analyses.

The paper identifies the GYS1 interactome in brown adipocytes using proximity labeling, revealing novel interactors and broader functional roles beyond glycogen synthesis.

This paper shows PCMTD1, a cullin-RING ligase, recognizes L-isoaspartyl residues and targets damaged proteins for ubiquitylation and degradation.

This study identifies BDH proteins as conserved subunits of plant SWI/SNF complexes, showing their role in complex stability and hypocotyl elongation through interactions with ARP4-ARP7.

The paper identifies a conserved CYC-YPMF motif in Pol IV critical for CLSY docking, essential for small RNA biogenesis and transposon silencing.

The paper analyzes the secreted proteome of oligodendrocytes and progenitor cells to reveal their roles in extracellular matrix formation and inflammation regulation.

This paper identifies SCFFBXL5 as a regulator of VHL stability and HIF1α-dependent hypoxia response.

The paper maps neurotransmitter receptor subtypes and protein complexes to synapses in Drosophila using molecular and connectomic techniques.

The paper investigates how microglia and the extracellular matrix influence cognitive aging by analyzing ECM composition, microglial interactions, and their relationship with synapses and behavior.