Ming S. Soh

This study uses different fluorescent labels to distinguish distinct kinetic components of S4 movement in the spHCN channel voltage sensor.

This study evaluates the therapeutic potential of Org 34167, an HCN channel inhibitor, for HCN1-DEE using multiple assays, showing efficacy in reducing cation leak and seizures but with side effects.

This study shows that atenolol reduces cardiac-related mortality in a genetic mouse model of SUDEP by mitigating seizure and LQTS interactions.

The paper identifies loss-of-function KCNH2 variants as enriched in SUDEP patients compared to epilepsy controls, suggesting a genetic biomarker for SUDEP risk.

This study shows that disrupting CMT2-associated genes in C. elegans causes similar movement, muscle, and neuromuscular junction defects.