Author

Antonio C. Ruzzini

University of SaskatchewanORCID 0000-0002-5697-5371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Iryna Myziuk· 2 shared Zahi MullaiD· 2 shared Albert Marinus BerghuisiD· 1 shared Bradon R. McDonaldiD· 1 shared Cameron R. CurrieiD· 1 shared Emma T. R. KellyiD· 1 shared Eric J. Caldera· 1 shared Ethan B. Van Arnam· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Iryna Myziuk

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 28, 2026

Characterization of a spiramycin-inactivating macrolide esterase

Iryna Myziuk, Zahi Mulla, Taslimun Jannat, Antonio C. Ruzzini

The paper characterizes EstS, a macrolide esterase from E. coli, showing it preferentially inactivates spiramycin and tylosin, explaining resistance phenotypes.

DOI 10.64898/2026.10.26.761979

E. colistatistical model

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedJul 15, 2026

Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases

Emma T. R. Kelly, Iryna Myziuk, Mark Hemmings…·Albert Marinus Berghuis

This study characterizes four Est-type macrolide esterases, revealing structural and functional insights into their substrate specificity and resistance mechanisms.

1 citation

experimental assay

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MicrobiologybioRxivPreprintFeb 10, 2019

Biogeography and Microscale Diversity Shape the Biosynthetic Potential of Fungus-growing Ant-associated Pseudonocardia

Bradon R. McDonald, Marc G. Chevrette, Jonathan L. Klassen…·Cameron R. Currie

The paper analyzes genetic diversity and biosynthetic potential in Pseudonocardia bacteria associated with fungus-growing ants across a 20km transect, revealing geographic and phylogenetic patterns of microbial diversity.

DOI 10.1101/545640

bacteria (other)DNA methylation

𝕏 PostBluesky