Author

Savina Apolloni

Department Biology, University of Rome Tor Vergata, Rome, ItalyORCID 0000-0002-5782-1665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ilaria Della ValleiD· 2 shared Martina MilaniiD· 2 shared Nadia D’AmbrosiiD· 2 shared Andrea Ninni· 1 shared Annalucia SerafinoiD· 1 shared Cinzia Volontè· 1 shared Daniele Lettieri-BarbatoiD· 1 shared Erica D’Avorio· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Ilaria Della ValleORCID

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2 papers

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedMar 29, 2025

Cytoplasmic accumulation of a splice variant of hnRNP A2/B1 contributes to FUS-associated toxicity in a mouse model of ALS

Simona Rossi, Martina Milani, Ilaria Della Valle…·Mauro Cozzolino

This study shows that FUS-induced splicing changes lead to cytoplasmic accumulation of hnRNP A2b/B1 splice variants, promoting stress granule formation and motor neuron toxicity in a mouse model of ALS.

6 citations

mouseexperimental assay

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PhysiologybioRxivOct 18, 2023

Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia

Francesca Sciarretta, Fabio Zaccaria, Andrea Ninni…·Daniele Lettieri-Barbato

This study shows that frataxin deficiency in microglia shifts metabolism to glucose catabolism, causing inflammation, which is mitigated by butyrate treatment.

DOI 10.26508/lsa.202402609

mousescRNA-seq

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