Author

Naomi Bronkema

Broad InstituteORCID 0000-0002-5787-2761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andi PaniD· 1 shared Baodan Hu· 1 shared Catrina A. SpruceiD· 1 shared Charles C. BaileyiD· 1 shared Christopher L. BakeriD· 1 shared Gogce C. CryneniD· 1 shared Gregory W. CarteriD· 1 shared Guruprasad AnandaiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Andi PanORCID

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2 papers

Recent·Most cited

BioengineeringNature Biomedical EngineeringPeer-reviewedDec 5, 2024

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4

Andi Pan, Charles C. Bailey, Tianling Ou…·Wenhui He

This study demonstrates that non-antibody protein biologics can undergo affinity maturation in vivo, leading to improved binding affinity and neutralization potency against HIV-1.

15 citations

mouseproteomics

𝕏 PostBluesky

GeneticsGenes & DevelopmentPeer-reviewedMar 1, 2020

HELLS and PRDM9 form a Pioneer Complex to Open Chromatin at Meiotic Recombination Hotspots

Catrina A. Spruce, Sibongakonke Dlamini, Guruprasad Ananda…·Christopher L. Baker

The paper shows HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hotspots, enabling DSB machinery access and preventing sterility in male mice.

85 citations

mouseChIP-seq

𝕏 PostBluesky