Author

Yuemin Bian

Broad InstituteORCID 0000-0002-5845-772XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Andrew G. StepheniD· 1 shared Andrew J. AguirreiD· 1 shared Andrew Lee HongiD· 1 shared Andrew O. GiacomelliiD· 1 shared Arvind RaviiD· 1 shared Barbara I. LudekeiD· 1 shared Belinda WangiD· 1 shared Christopher T. LemkeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Andrew G. StephenORCID

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2 papers

Recent·Most cited

MicrobiologyCellPeer-reviewedJan 20, 2025

Structural and functional analysis of the Nipah virus polymerase complex

Side Hu, Heesu Kim, Pan Yang…·Jonathan Abraham

This study determines the cryo-EM structure of the Nipah virus polymerase complex and identifies key domains critical for replication and transcription.

42 citationstop 1%

viruscryo-EM

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Cancer BiologybioRxivPreprintOct 22, 2024

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity

Jason J. Kwon, Julien Dilly, Shengwu Liu…·Andrew J. Aguirre

This study uses deep mutational scanning to analyze KRAS variants, identifying gain- and loss-of-function mechanisms and their impact on oncogenic activity.

13 citations

humanproteomics

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