Author

Graham Coutts

Manchester Academic Health Science CentreORCID 0000-0002-5865-9495Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Stuart McRae AllaniD· 2 shared Andrew J. TrevelyaniD· 1 shared Antony D. AdamsoniD· 1 shared Catherine B. LawrenceiD· 1 shared Christopher HoyleiD· 1 shared Connie Mackenzie‐Gray ScottiD· 1 shared David BroughiD· 1 shared Dhifaf A. JasimiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Stuart McRae AllanORCID

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3 papers

Recent·Most cited

ImmunologyDisease Models & MechanismsPeer-reviewedMar 4, 2026

Inflammatory responses following CRISPR modification of the nuclear localisation sequence in endogenous interleukin-1α

Christopher Hoyle, Rodrigo Diaz Pino, Si Min Lai…·Gloria López‐Castejón

This study disrupts the nuclear localisation sequence of endogenous IL-1α in mice and examines its effects on inflammatory responses, finding no significant changes in LPS-induced transcriptional signatures or IL-1 release.

1 citation

mouseproteomics

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NeurosciencebioRxivPreprintMar 7, 2022

Targeting neuronal homeostasis to prevent seizures

Fred Mulroe, Wei‐Hsiang Lin, Connie Mackenzie‐Gray Scott…·Richard Baines

This study identifies a novel anticonvulsant compound that targets neuronal homeostasis by increasing Pumilio expression, showing efficacy in Drosophila and mouse seizure models.

DOI 10.1101/2022.03.07.483229

Drosophilamouse

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NeuroscienceACS NanoPeer-reviewedNov 6, 2019

Selective Liposomal Transport Through Blood Brain Barrier Disruption in Ischaemic Stroke Reveals Two Distinct Therapeutic Opportunities

Zahraa S. Al-Ahmady, Dhifaf A. Jasim, Sabahuddin Syed Ahmad…·Kostas Kostarelos

This study shows liposomes can selectively enter the brain after stroke through two distinct BBB disruption phases, offering new therapeutic opportunities for targeted drug delivery.

108 citationstop 5%

mouseexperimental assay

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