Kyle M. Walsh

The paper evaluates a reproductive genetic screening framework that includes genes with perinatal intervention potential, finding an individual-level number-needed-to-screen of 3.20 using gnomAD and 3.62 using All of Us.

This study analyzes a diverse glioma cohort to show ancestry influences on survival, somatic alterations, and mutational processes in diffuse gliomas.

This study investigates associations between infant genetic diagnoses and pregnancy complications, finding elevated risks of gestational diabetes, preeclampsia, and placental disorders.

This study shows that intracranial tumors cause systemic sympathetic hyperactivity, impairing T cell function and limiting immunotherapy, and that beta-adrenergic blockade improves outcomes in mouse models and human patients.

The paper integrates GWAS and PheWAS data to identify genetic links between Alzheimer's disease and platelet traits, finding pleiotropy and a novel risk locus near EGFR.