Survival of the unfittest: clinical emergence of hyper-multidrug-resistant Nakaseomyces glabratus with rare nonfunctional Erg3 and Erg11 and severely impaired fitness.
Hans Carolus, Vladislav V. Biriukov, Jolien Vreys…·Patrick Van Dijck
The paper identifies hyper-multidrug-resistant Nakaseomyces glabratus strains with fitness trade-offs and explores nitroxoline as a potential alternative therapy for resistant UTIs.