Author

Matthew J. Seasock

Baylor College of MedicineORCID 0000-0002-5940-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Phillip A. EriceiD· 2 shared Shivani L. Lotlikar· 2 shared Adriana M. HungiD· 1 shared Alexandre F. CariseyiD· 1 shared Anton James EnrightiD· 1 shared Antony RodrigueziD· 1 shared Antony RodrígueziD· 1 shared Benjamin F. VoightiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Phillip A. EriceORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedMay 10, 2025

Let-7 restrains an oncogenic circuit in AT2 cells to prevent fibrogenic cell intermediates in pulmonary fibrosis

Matthew J. Seasock, Md Shafiquzzaman, Maria Elisa Ruiz Echartea…·Antony Rodriguez

This study identifies let-7 as a regulator of AT2 cell differentiation and fibrosis prevention by controlling oncogenic networks and epigenetic changes.

23 citationstop 2%

mouseATAC-seq

𝕏 PostBluesky

ImmunologyeLifePeer-reviewedFeb 7, 2024

Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt

Phillip A. Erice, Xinyan Huang, Matthew J. Seasock…·Antony Rodríguez

This study shows that downregulation of let-7 miRNA promotes Tc17 differentiation and emphysema by de-repressing RORγt in mice.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky

GeneticsNature GeneticsPeer-reviewedAug 12, 2021

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma…·Katalin Suszták

The paper maps genetic variants to cell types in the kidney to identify disease mechanisms and drug targets.

161 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky