Author

Sina Stäble

German Cancer Research CenterORCID 0000-0002-5962-2440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Daniel B. LipkaiD· 3 shared Maximilian SchönungiD· 3 shared Pavlo LutsikiD· 3 shared Jens LangsteiniD· 2 shared Joschka HeyiD· 2 shared Mariam HakobyaniD· 2 shared Mark HartmanniD· 2 shared Matthias SchlesneriD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Daniel B. LipkaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyBlood Cancer DiscoveryPeer-reviewedDec 5, 2025

Oncogenic RAS-Pathway Activation Drives Oncofetal Reprogramming and Creates Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia

Mark Hartmann, Maximilian Schönung, Jovana Rajak…·Daniel B. Lipka

This study identifies oncofetal reprogramming in juvenile myelomonocytic leukemia, linking RAS-pathway activation to fetal gene expression and revealing CD52 as a therapeutic target.

9 citationstop 5%

humanbulk RNA-seq

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GenomicsExperimental HematologyPeer-reviewedNov 8, 2022

Dynamic DNA methylation reveals novel cis-regulatory elements in murine hematopoiesis

Maximilian Schönung, Mark Hartmann, Stephen Krämer…·Daniel B. Lipka

The paper develops a computational framework for analyzing DNA methylation data in mouse hematopoiesis, identifying novel cis-regulatory elements associated with gene expression during differentiation.

8 citations

mouseDNA methylation

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BioinformaticsEpigeneticsPeer-reviewedOct 24, 2020

AmpliconDesign - An interactive web server for the design of high-throughput targeted DNA methylation assays

Maximilian Schönung, Jana Hess, Pascal Bawidamann…·Daniel B. Lipka

AmpliconDesign provides a web server for designing high-throughput targeted DNA methylation assays, improving primer design and analysis workflows for epigenetic studies.

6 citations

DNA methylationexperimental assay

𝕏 PostBluesky