Author

Joschka Hey

German Cancer Research CenterORCID 0000-0003-2842-764XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Christoph PlassiD· 3 shared Daniel B. LipkaiD· 3 shared Pavlo LutsikiD· 3 shared Dieter WeichenhaniD· 2 shared Jens LangsteiniD· 2 shared Maximilian SchönungiD· 2 shared Sina StäbleiD· 2 shared Abdul‐Habib MaagiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

Christoph PlassORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cell BiologyEMBO Molecular MedicinePeer-reviewedFeb 23, 2026

Epigenetic deregulation of IFN and WNT pathways in AT2 cells impairs alveolar regeneration (in COPD)

Maria Llamazares Prada, Uwe Schwartz, Darius F. Pease…·Renata Zofia Jurkowska

This study identifies epigenetic changes in AT2 cells from COPD patients that disrupt IFN and WNT pathways, impairing lung regeneration.

5 citations

humanbulk RNA-seq

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Cancer BiologyBlood Cancer DiscoveryPeer-reviewedDec 5, 2025

Oncogenic RAS-Pathway Activation Drives Oncofetal Reprogramming and Creates Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia

Mark Hartmann, Maximilian Schönung, Jovana Rajak…·Daniel B. Lipka

This study identifies oncofetal reprogramming in juvenile myelomonocytic leukemia, linking RAS-pathway activation to fetal gene expression and revealing CD52 as a therapeutic target.

9 citationstop 5%

humanbulk RNA-seq

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Cancer BiologyBlood AdvancesPeer-reviewedAug 9, 2024

Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

Dieter Weichenhan, Anna Riedel, Etienne Sollier…·Christoph Plass

The paper shows MNX1 overexpression in t(7;12)(q36;p13) AML is due to enhancer hijacking, not oncofusion, and is common in pediatric cases.

17 citationstop 4%

humanbulk RNA-seq

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BioinformaticsEpigeneticsPeer-reviewedOct 24, 2020

AmpliconDesign - An interactive web server for the design of high-throughput targeted DNA methylation assays

Maximilian Schönung, Jana Hess, Pascal Bawidamann…·Daniel B. Lipka

AmpliconDesign provides a web server for designing high-throughput targeted DNA methylation assays, improving primer design and analysis workflows for epigenetic studies.

6 citations

DNA methylationexperimental assay

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