Author

Eric Gelsleichter

Cornell UniversityORCID 0000-0002-5970-813XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Erik K. HenzeiD· 2 shared Toshimitsu KawateiD· 2 shared Bennett William FoxiD· 1 shared Frank C. SchroederiD· 1 shared Hening LiniD· 1 shared Jacqueline J. EhrlichiD· 1 shared Janice RobertsoniD· 1 shared Jordyn M. BoeschiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Erik K. HenzeORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedDec 13, 2024

The C-terminal activating domain promotes Panx1 channel opening

Erik K. Henze, Jacqueline J. Ehrlich, Janice Robertson…·Toshimitsu Kawate

This paper identifies the C-terminal activating domain (CAD) as essential for Panx1 channel opening, showing how its cleavage repositions the N-terminus to reduce anion accumulation and promote ion permeability.

18 citationstop 3%

experimental assaycell signaling & trafficking

𝕏 PostBluesky

BiophysicsbioRxivOct 23, 2023

ATP-release pannexin channels are gated by lysophospholipids

Erik K. Henze, Russell N. Burkhardt, Bennett William Fox…·Toshimitsu Kawate

The paper identifies lysophospholipids as activators of pannexin channels, showing they trigger ATP and other metabolite release, and activate inflammasomes in human monocytes.

6 citations

mousehuman

𝕏 PostBluesky