NeurosciencebioRxivPreprint
Multi-OMIC analysis of brain and serum from chronically-stressed mice reveals network disruptions in purine metabolism, fatty acid beta-oxidation, and antioxidant activity that are reversed by antidepressant treatment
Peter J. Hamilton, Emily Y. Chen, Vladimir Tolstikov…·Eric J. Nestler
The paper analyzes multi-omic data from stressed mice to identify molecular disruptions linked to depression and shows antidepressants reverse these changes in specific brain regions.
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