Per-Eric Lund

The paper investigates δ-cell function in type-2 diabetes, finding that these cells become resistant to inhibition, leading to hyperactivity and impaired glucose control.

This study shows that RFX6 haploinsufficiency impairs beta cell function, leading to reduced insulin secretion and increased diabetes risk.

This study generates and benchmarks functionally mature stem cell-derived islets, showing they closely resemble primary adult islets in transcriptional and functional properties.