Michael J. Smanski

This study improves perennial ryegrass transformation by using developmental regulator genes, enabling efficient plant regeneration across genotypes.

The paper engineers Drosophila melanogaster to express microbial nitroreductases for TNT degradation screening, finding cofactor-dependent activity in fly lysates.

The paper models how growth rate affects selection for costly toxin production in microbes, finding stronger selection at higher growth rates in spatially-structured environments.

The paper investigates genetic design constraints in domesticated Influenza A Virus for transient gene delivery, identifying permissible mutations and RNA level motif depletion.

The paper introduces the Natural Products Discovery Center, releasing 8490 sequenced Actinobacteria strains and highlighting their taxonomic and biosynthetic diversity.

This paper demonstrates a method to create engineered genetic incompatibilities in Drosophila melanogaster that can be tuned to cause hybrid lethality and are compatible with other engineered strains.

The paper describes a method to produce non-genetically engineered male insects for SIT programs through batch cultivation, achieving high sex-selection rates without genetic modification.

This study simulates a genetic control strategy for Aedes aegypti that combines incompatibility and female-lethality to suppress populations more effectively than gene drives.

The paper engineers a genetic barrier to sexual reproduction by using programmable transcription factors to induce lethal gene expression in hybrid offspring.