Marzia Rossato

This study validates allele-specific LMNB1 silencing in patient-derived astrocytes as a therapeutic approach for ADLD by showing restored physiological levels and functional improvements.

This study shows that enhanced non-photochemical quenching (NPQ) in Haematococcus lacustris improves high-light tolerance under carbon limitation but reduces growth and astaxanthin productivity under high CO2 conditions.

The paper investigates how genetic variation in common bean affects plant-plant interactions with maize, showing that effects depend on neighbor identity and environmental context.

The paper validates long-read sequencing methods for analyzing repeat expansions in DM2, identifying new repeat motifs and improving bioinformatic workflows.

The paper develops a portable sequencing workflow for in situ microbial community analysis in rivers, combining autonomous sampling with field and lab sequencing to reduce costs and improve temporal resolution.

This study identifies adaptive gene loss in common bean populations during range expansion and domestication, showing gene loss as a key adaptive trait.

The paper identifies genotype-environment associations and adaptive variation in chickpea along historical Silk Road routes, highlighting genes related to heat and drought tolerance.

The paper analyzes gene expression in tetraploid wheat under different nitrogen conditions to identify selection signatures during domestication.

This study uses chloroplast and nuclear genomes to trace the evolutionary history of common beans, supporting a Mesoamerican origin and rejecting a new species classification.

This paper uses CRISPR/Cas9 to deplete repetitive DNA in lentil genomes, improving genotyping accuracy and efficiency by focusing sequencing on single-copy regions.

This study characterizes full-length CNBP repeat expansions in DM2 patients using Cas9-mediated nanopore sequencing, revealing novel repeat patterns and mosaicism.

The paper analyzes structural variants in Nebbiolo grapevines across individual, clonal, and cultivar levels using long-read and optical mapping data.

The paper performs whole-exome sequencing on mummified remains to identify a genetic mutation associated with late-onset Pompe disease in a historical figure.

The paper evaluates how DNA fragment length and enrichment technology affect genotypability in whole-exome sequencing, finding that longer fragments improve callable bases and genotypability across different platforms.

The paper identifies PvMYB26 as a candidate gene for pod indehiscence in common bean, linking its fine regulation to the absence of a functional abscission layer.

This paper introduces a portable workflow for on-site DNA barcoding using MinION sequencing and ONTrack pipeline, achieving high accuracy and low computational demand for field biodiversity tracking.