José Luís Rosa

This study identifies HERC1 substrates through proteomic analysis, revealing its role in proteasome homeostasis and linking its dysfunction to neurodevelopmental disease.

This study shows that HERC1 loss causes neurodevelopmental abnormalities in mice, including hippocampal dysfunction and sex-dependent synaptic defects.

This study confirms that PI3K inhibition with BYL719 prevents heterotopic ossification by blocking osteochondroprogenitor specification and reducing inflammation.