Vera L. Bonilha

This study shows that mtDNA mutations in mice lead to metabolic dysfunction in the retina and RPE, impairing retinal function through altered energy metabolism and glucose transport.

This study investigates how DJ-1 deficiency and aging jointly impact mitochondrial function in the retina and RPE, showing reduced OXPHOS complex levels and increased mtDNA damage.

This study uses a POLG deficiency model to show that mtDNA mutations cause retinal degeneration through impaired mitochondrial function and accelerated aging.