Abbas Maqbool

This study identifies a conserved NLR activation switch in bacterial AfsR that regulates antibiotic biosynthesis and reveals its evolutionary conservation across Actinomycetota.

This paper designs de novo integrated domains using AI tools to enable plant NLR receptors to recognize non-cognate pathogen effectors, demonstrating functional immune responses and structural fidelity.

The paper investigates the evolution of APikL virulence effectors in the blast fungus by combining ancestral reconstruction and functional assays, finding that only one substitution expanded host binding while others were deleterious.

This study identifies a CTP-independent ParABS system in Streptomyces coelicolor that segregates plasmid SCP2 through a ParT protein that diffuses on DNA without CTP binding or hydrolysis.

This study identifies a bacterial immune system, LypABC, that controls GTA release in Caulobacter crescentus by coupling GTA activation with host cell lysis.

This study identifies Mp10, an aphid saliva CSP effector, which suppresses plant PTI by interacting with AMSH deubiquitinases and modulating PRR kinase trafficking.

This study shows how the helper NLR NRC2 converts from a homodimer to a higher-order oligomer upon activation by the sensor NLR Rx, revealing the molecular mechanism of plant immune activation.

This paper shows how a parasite effector protein manipulates host developmental processes by hijacking a ubiquitin receptor to induce phenotypic changes.