M. Waleed Gaber

This study examines transcriptional and DNA methylation changes in the hippocampus and prefrontal cortex of irradiated mice, identifying cell-type-specific gene expression and methylation patterns linked to cognitive deficits.

The paper shows that combining anti-CSF-1R therapy with chemotherapy and anti-PD-1 improves immune response in metastatic TNBC by reducing macrophages and increasing T/B cell infiltration.

The paper identifies lncRNAs that coordinately regulate both transcription and post-transcriptional processing of their targets, showing tight coupling between lncRNA and target abundance, with implications for cancer gene regulation.