Douglas L. Crawford

The paper shows that a single generation of natural selection in a heterogeneous habitat can cause significant phenotypic divergence among individuals in the same population.

The paper identifies trans-acting eQTLs driving mRNA expression linked to physiological traits in killifish, showing most eQTLs are trans-acting rather than cis-acting.

The paper uses mRNA expression data from fish populations acclimated to different temperatures to explain variation in physiological traits, finding tissue-specific co-expression patterns that explain up to 82% of trait variation.