Stephen Tomlinson

This study shows that aging increases microglia inflammation and phagocytosis in the adult SVZ niche, reducing progenitor proliferation and SVZ neurogenesis.

This study identifies vascular luminal glycocalyx loss and complement activation as key drivers of BBB injury in hyperglycemic stroke, showing that targeting complement after reperfusion improves outcomes.

This study shows that targeting complement C3 with gene therapy reduces neurodegeneration in glaucoma by protecting retinal ganglion cells.