Sarah Anderson

The paper identifies CD11c-expressing microglia as a transient state in the developing retina driven by interactions with apoptotic cells, not a specialized subset for phagocytic clearance.

This study shows that microglial cathepsin B is essential for efficient neuronal efferocytosis during brain development, preventing apoptotic cell accumulation and ensuring proper neural circuit formation.

This study identifies a Type I interferon-responsive microglial subset that engulfs neurons during brain development and shows its role in shaping cortical structure and behavior.

This study shows that targeting complement C3 with gene therapy reduces neurodegeneration in glaucoma by protecting retinal ganglion cells.