Jan Zarzycki

The paper reconstructs minimal pyrenoids using EPYC1 proteins to study their evolution and carbon concentration mechanisms.

This study enhances Fe-nitrogenase's ability to convert CO2 to hydrocarbons through directed evolution, increasing CH4 production and expanding the product spectrum to include ethane and CO.

The paper identifies Form IF Rubiscos that are highly active, specific, and function without the small subunit, challenging the necessity of subunit complexity in Rubisco evolution.

This study presents the first molecular structure of methylthio-alkane reductase, revealing metalloclusters that inform its function and evolutionary relationship to nitrogenases.

The paper shows that multiple mechanisms of essentiality in protein-protein interactions can persist over time, even if individual mechanisms are lost, using Rubisco as a case study.