Simon Léonard

This study identifies how lymphoma B cells alter bone marrow stromal cell organization and function, creating a supportive cancer-associated fibroblast network in follicular lymphoma.

This study shows that signals from the bone marrow B cell niches influence pre-leukemic cell fate in murine B-ALL by altering proliferation and secondary mutation patterns.

This study identifies mutations in the IgG heavy chain in follicular lymphoma and EZB DLBCL that enhance BCR signalling and oncogenicity by disrupting the IgG intracellular tail.

The paper maps the single-cell transcriptome of human fetal gonads to define somatic cell lineage specification during development.

FlexDotPlot is an R package that generates dot plots for multifaceted data, including single-cell RNA-seq, with an interactive Shiny app for non-R users.

This paper sequenced the genome of Dickeya aquatica, showing its pathogenic potential and revealing evolutionary dynamics in Dickeya species.