Pål Jarle Johnsen

The paper uses long-read sequencing to analyze plasmids and chromosomes in E. coli over two decades, revealing long-term plasmid-lineage associations and success strategies.

The paper identifies mutations in the enzyme MbaA that enhance c-di-GMP synthesis, promoting biofilm formation in Vibrio cholerae by disrupting polyamine regulation.

The paper shows plasmids can cause microindel mutations in Acinetobacter baylyi by generating single-stranded DNA that integrates into the genome, with some plasmids suppressing mutations.

This study shows that DprA and RecFOR suppress microindel mutations in Acinetobacter baylyi by inhibiting SPDIR, a rare mutation mechanism, and reveals DprA's antimutational role independent of its transformation function.

This study shows that biofilm lifestyle selects for mutations in β-lactamases that reduce biofilm inhibition while maintaining antibiotic resistance.

The paper introduces a computational pipeline for consistent plasmid typing using long-read sequencing data, enabling classification of novel and known plasmid types.

This study shows that β-lactamases from different Ambler classes confer cefiderocol resistance and can evolve to increase resistance through mutations.