Klaus Harms

The paper uses long-read sequencing to analyze plasmids and chromosomes in E. coli over two decades, revealing long-term plasmid-lineage associations and success strategies.

The paper shows plasmids can cause microindel mutations in Acinetobacter baylyi by generating single-stranded DNA that integrates into the genome, with some plasmids suppressing mutations.

This study shows that DprA and RecFOR suppress microindel mutations in Acinetobacter baylyi by inhibiting SPDIR, a rare mutation mechanism, and reveals DprA's antimutational role independent of its transformation function.