Author

Shota Imai

Kanazawa UniversityORCID 0000-0002-6550-1514Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:multiome· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Makie Ueda· 3 shared Rikinari HanayamaiD· 3 shared Toan Van Le· 3 shared Tomoyoshi YamanoiD· 3 shared Iriya Fujitsuka· 2 shared Kazutaka Matoba· 2 shared Ayano Ikebuchi· 1 shared Dilireba Bolidong· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Makie Ueda

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 21, 2026

Modular mRNA platform for in vivo antigen-specific immune tolerance

Shota Imai, Naoto Nishida, Ryo Maeno…·Tomoyoshi Yamano

This paper introduces Tol-mRNA, a modular mRNA platform that induces antigen-specific immune tolerance by delivering PD-L1 and TGF-β along with antigen, showing therapeutic benefits in murine models and human immune settings.

DOI 10.64898/2026.05.18.725807

mousehuman

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 16, 2025

mRNA-Based Designer APCs Elicit Robust CD8⁺ and CD4⁺ T Cell Responses

Toan Van Le, Shota Imai, Iriya Fujitsuka…·Tomoyoshi Yamano

This paper develops an mRNA-based platform that reprograms somatic cells into designer APCs, enhancing T cell responses against tumors and demonstrating translational potential in human and mouse models.

DOI 10.1101/2025.09.16.676697

humanmouse

𝕏 PostBluesky

BioengineeringbioRxivPreprintSep 25, 2023

Surface-engineered extracellular vesicles to modulate antigen-specific T cell expansion for cancer immunotherapy

Xiabing Lyu, Tomoyoshi Yamano, Shota Imai…·Rikinari Hanayama

The paper develops antigen-presenting extracellular vesicles (AP-EVs) engineered to enhance T cell expansion and anticancer immunity through combined immunotherapy.

1 citation

experimental assaycancer & tumor microenvironment

𝕏 PostBluesky