Ruth A. Franklin

The paper shows that type I interferon primes alveolar epithelial cells for regeneration by enhancing their response to reparative signals from tissue-resident macrophages after viral infection.

The paper identifies Kat8 and the NSL complex as essential for lung epithelial repair and maps transcription factor dependencies in alveolar repair trajectories using SAGE.

This study shows that airway injury triggers alveolar type 2 cell proliferation mediated by macrophages, revealing a myeloid-driven response in the lung.

This study shows TRPV1+ sensory neurons protect against influenza by modulating myeloid cell responses and reducing immunopathology.

This study identifies macrophage-derived Oncostatin M as a critical regulator of type I interferon responses during viral respiratory infection, preventing excessive inflammation.

This study identifies a cell-circuit framework for wound healing and fibrosis, revealing three fibrosis outcomes and parameters that control the transition from healing to fibrosis.