Author

Alex Severino

Johns Hopkins UniversityORCID 0000-0002-6567-8133Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Elizabeth D. LuczakiD· 2 shared Oscar E. Reyes GaidoiD· 2 shared Ahmed M. A. Abd El-Karim· 1 shared An‐Chi WeiiD· 1 shared Bian LiuiD· 1 shared Erick O. Hernández‐OchoaiD· 1 shared Gabriel A. Lopez-CecetaiteiD· 1 shared Giovanni Rosales‐SotoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Elizabeth D. LuczakORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 11, 2025

Cell type specific CaMKII activation patterns revealed by CaMKAR, a bioactivity reporter deployable in living cells

Alex Severino, Oscar E. Reyes Gaido, Bian Liu…·Elizabeth D. Luczak

The paper uses a CaMKII activity reporter to study activation patterns in cardiac, skeletal muscle, and neurons, revealing differences in activation rates and subcellular localization.

2 citations

experimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintSep 23, 2024

SGLT2 inhibitors protect against diabetic cardiomyopathy and atrial fibrillation through a CaMKII independent mechanism

Alex Severino, Oscar E. Reyes Gaido, Pauline Nguyen…·Olurotimi O. Mesubi

This study shows SGLT2 inhibitors reduce diabetic cardiomyopathy and atrial fibrillation risk in T2D mice, but their effects are not dependent on CaMKII inhibition.

2 citations

mouseexperimental assay

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