Laurence M Morel

This study shows that inhibiting glycolysis with 2DG reduces TFH cell expansion and autoantibody production in lupus-prone mice, with potential therapeutic implications for SLE.

This study shows that glutaminolysis supports lupus Tfh cell function, and its inhibition reduces autoantibody production and disease in lupus-prone mice.

The paper shows that dietary tryptophan and genetic factors shape gut microbiota, which in turn influence autoimmune activation in lupus.