Jan Christoph Thiele

This paper introduces a method for continuous mass photometry of single molecules, enabling long-term observation of biomolecular interactions with high mass precision and temporal resolution.

This paper introduces a method using mass photometry with supported lipid bilayers to detect and measure proteins in complex mixtures without prior purification.

This paper introduces modular DNA nanosensors that enable label-free, multiplexed single-molecule mass photometry to resolve protein biochemical states in complex media without washing or immobilisation.

This paper introduces a deep learning method to classify mass photometry events, improving single-molecule mass measurement accuracy by reducing artifacts and enhancing resolving power.

This paper provides guidelines for optimizing mass photometry to achieve high mass resolution and detection limits while maintaining simplicity.

This paper combines FL-SMLM with ISM to improve lateral localization accuracy and eliminate chromatic aberration in single-molecule imaging.

This paper introduces MIET-PAINT, a method combining DNA-PAINT and Metal-Induced Energy Transfer to achieve nanometer-scale 3D imaging with high multiplexing capability.

This paper demonstrates single-protein mass measurement using a dark-field scattering microscope with non-common path geometry, achieving five orders of magnitude higher sensitivity than previous methods.