Alternative polyadenylation regulates human urothelial differentiation
N.T. Le, Surbhi Sona, Briana A. Santo…·Angela H. Ting
The paper investigates how alternative polyadenylation (APA) regulates urothelial differentiation using single-cell RNA-seq and spatial imaging, showing APA's role in shaping cell state-specific polyadenylation sites and transcriptome diversity.