Booki Min

This study identifies the Lag3 KIEELE motif as essential for Treg cell suppression by linking HPK1 signaling to metabolic and functional regulation.

This study shows that IL-27 limits HSPC differentiation during infection and prevents stem cell exhaustion by reducing monocyte production and maintaining HSPC function.

This study uses single-cell RNA sequencing to identify a CD6/ALCAM-mediated immune-suppressive pathway in recurrent NMIBC, suggesting CD6 as a potential therapeutic target.

This study identifies impaired type I IFN and IL-27 signaling in RRMS Tregs and shows that cGAMP-MPs restore Treg suppressive function in EAE.

This study identifies miR-342 as a master regulator of glycolysis in Foxp3+ regulatory T cells, essential for controlling inflammation in the central nervous system.

The paper uses single-cell RNA sequencing to analyze lung-infiltrating Tregs in eosinophilic and neutrophilic allergic airway inflammation models, revealing significant heterogeneity and tissue-residency differences.

The paper maps cell types, architecture, and signaling networks in the human ureter using single-cell and spatial transcriptomics to inform tissue engineering strategies.