Pierre Julius Magistretti

The paper establishes the Saudi Bank of Induced Pluripotent Stem Cells (SBiPSCs) to address underrepresentation of Middle Eastern populations in iPSC resources and supports immunocompatible cell therapies.

This study shows lactate extends C. elegans lifespan via redox-driven lipid remodeling and involves SIRT1 and RICTOR.

This study shows lactate enhances NMDA receptor currents through redox-sensitive cysteines in GluN2B and CaMKII interactions, linking astrocyte metabolism to synaptic plasticity.

This study shows that LPA16:0, derived from platelets, reduces adult neurogenesis and stress resilience in anxiety disorders by activating LPA1 receptors.

Ultraliser creates high-fidelity 3D models of neuroscientific structures for in silico simulations, enabling detailed structural analysis and scalable experiments.

This paper conducts a multi-ancestry GWAS meta-analysis of suicide attempt, identifying 12 genome-wide significant loci and finding shared genetic risks with ADHD, smoking, and risk tolerance.

The paper shows lactate and glucose are differentially used for neuronal fueling based on memory load and engram complexity.

The paper digitally reconstructs the neuro-glia-vascular system in rat somatosensory cortex to understand astrocyte-vascular-neuron interactions and their anatomical constraints.

The paper studies spike-frequency adaptation in a Hodgkin-Huxley-type model, showing how Na,K-ATPase and calcium-dependent potassium channels interact to shape neuronal firing patterns.

The paper shows lactate and pyruvate enhance stress resistance and longevity via ROS signaling in neuroblastoma cells and C. elegans.

This paper uses transcriptomic imputation to identify gene-tissue associations linked to Anorexia Nervosa risk, finding significant links in both brain and metabolic tissues.