BiochemistryJournal of Clinical InvestigationPeer-reviewed
Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate
Eric D. Queathem, David B. Stagg, Alisa B. Nelson…·Peter A. Crawford
Author
Jacob R. Gillingham
University of MinnesotaORCID 0000-0002-6717-9960Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2025 · peak 2/yrCo-Author Collaboration Network
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Recent·Most cited
- BiochemistryScience AdvancesPeer-reviewed
Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation
Eric D. Queathem, Zahra Moazzami, David B. Stagg…·Patrycja Puchalska
The paper shows ketogenesis supports PUFA homeostasis in hepatocytes by enabling FA elongation, and its disruption leads to lipid imbalances similar to MASLD.
32 citationstop 1% - BiochemistryACS Infectious DiseasesPeer-reviewed
kinact/KI Value Determination for Penicillin-Binding Proteins in Live Cells
Joshua D. Shirley, Jacob R. Gillingham, Kelsie M. Nauta…·Erin E. Carlson
The paper develops a whole-cell assay to measure kinact/KI values for PBPs in Streptococcus pneumoniae, showing results consistent with in vitro data and supporting its validity as an in vivo method.