Key Regulatory Elements of the TGFbeta-LRRC15 Axis Predict Disease Progression and Immunotherapy Resistance Across Cancer Types
Michael Cheng, Claire M. Storey, Mohamed Altai…·David Ulmert
Author
The University of Texas MD Anderson Cancer CenterORCID 0000-0002-6806-1294Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
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Michael Cheng, Claire M. Storey, Mohamed Altai…·David Ulmert
Claire M. Storey, Mohamed Altai, Katharina Lückerath…·David Ulmert
This paper develops a radio-theranostic approach targeting LRRC15 to image and treat cancer, showing tumor reduction and reversal of immunotherapy resistance.
Bilal Ahmed Siddiqui, Nicolas L. Palaskas, Sreyashi Basu…·Sumit Kumar Subudhi
The paper uses single-cell RNA sequencing to identify molecular pathways and immune subsets in immune-related myocarditis and myositis, finding clonally expanded CD8+ T cells and specific myeloid cell populations associated with adverse outcomes.