Michael Cheng

This paper develops a radio-theranostic approach targeting LRRC15 to image and treat cancer, showing tumor reduction and reversal of immunotherapy resistance.

This study shows TMAO affects cell type-specific pathways in mouse aorta, promoting atherosclerotic plaque instability by increasing apoptosis and reducing ECM formation.

The paper identifies presynaptic and postsynaptic risk genes and key connectomes involved in pathological α-synuclein spreading using mathematical models and gene regulatory network analysis.

The paper investigates the interaction between mild traumatic brain injury and genetics to identify pathway and network-level effects on learning and memory in adolescents using the ABCD cohort.

This study shows T4 treatment alters cell-type specific genes, pathways, and networks in hippocampus and frontal cortex after mTBI, reversing mTBI-affected genes and pathways.