René Hägerling

This paper develops an endothelial graft-enhanced CAM tumor model to study T cell recruitment and activation in human cancer immunotherapy.

The paper develops a nanobody-based method to label kidney lymphatic vessels in mice, revealing spatially restricted LYVE1 expression unique to the kidney.

The paper compares bat and mouse limb development using single-cell analyses to show how a conserved gene program is repurposed in bat wing formation.

The paper identifies a unique pericystic endothelium in ADPKD that contributes to microvascular remodelling and impaired perfusion, suggesting vascular targets for early intervention.

This study identifies mesenchymal Osr1+ cells as regulators of embryonic lymphatic vessel formation by controlling LEC proliferation and migration.

The paper uses single-cell RNA sequencing to systematically phenotype mouse genetic models, identifying molecular and cellular changes across multiple mutants and wildtypes.