Nazanin Farahi

This study identifies the RNA-binding region of the androgen receptor and shows how lncRNA binding modulates interdomain communication and phase separation, contributing to ligand-independent AR signaling in prostate cancer.

The paper identifies oncogenic fusion proteins that drive cancer by forming ectopic condensates that dysregulate transcription.

The paper examines the concentration sensitivity of proteins involved in liquid-liquid phase separation and argues that in vitro concentrations are reasonable given cellular dosage sensitivity.